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AATB NEWS
Happy Holidays From AATB
As 2025 comes to a close, AATB would like to wish its members, partners, and other industry professionals a safe and happy holiday season. As we reflect on the past year for the industry, we would like to provide the readers of the AATB NewsBrief a look at some of the most accessed articles from the year. Our regular publication will resume Wednesday, January 7.
NEWS FROM THE FIELD
Uncovering How Cells Build Tissues and Organs
University of Rochester
Researchers are investigating how mechanical signals and the extracellular matrix guide tissue and organ development, aiming to uncover principles that could advance understanding of developmental diseases and regenerative medicine. Vanderbilt-Developed AI Platform Validated for Molecular Mapping of Tissue
VUMC News
Vanderbilt University Medical Center's AI platform iSCALE enables high-resolution molecular mapping of entire tissue sections, enhancing spatial biology by inferring gene expression from limited samples and revealing cellular features previously undetectable with conventional methods.
From Challenges to Solutions: The Promise of Regenerative Medicine and Tissue Engineering in Restoring Female Reproductive Health
ScienceDirect
Advances in biomaterials, stem cells, 3D bioprinting, and organoids are driving progress in creating functional reproductive tissues. Progress in Engineering Functional Cardiac Tissues from iPSC-Derived Cardiomyocytes: Advances in Construction and Applications
Science Direct
Advances in engineering cardiac tissues using iPSC-derived cardiomyocytes are enabling more accurate disease modeling, drug screening, and regenerative therapies, though challenges like cell immaturity and poor vascularization still limit clinical translation.
Signpost of Cancer Linked to Wound-Healing Properties
ASU News
SerpinB3, a protein long associated with cancer, has been found to play a crucial role in the body's natural wound-healing process, potentially paving the way for new treatments for chronic wounds and cancer. Stem Cell Therapy Helps AMD Patients See Again
ScienceDaily
Early-stage clinical trials show that adult stem cell transplants can safely restore significant vision improvements in patients with advanced dry age-related macular degeneration, offering hope for a future regenerative treatment.
NIH Researchers Use 3D Bioprinting to Create Eye Tissue
TCT Magazine
Using patient stem cells and 3D bioprinting, NIH researchers have created eye tissue that mimics the outer blood-retina barrier, offering a model for studying and potentially treating degenerative eye diseases like age-related macular degeneration. Research Breakthrough Could Help Regrow Lost Limbs
Texas A&M Stories
Researchers at Texas A&M University have identified fibroblast growth factor 8 (FGF8) as a key protein capable of regenerating an entire finger joint, marking a major step toward the possibility of full-limb regeneration in humans. Cardiac Repair and Regeneration: Cell Therapy, In Vivo Reprogramming, and the Promise of Extracellular Vesicles
Experimental & Molecular Medicine
Stem-cell-derived extracellular vesicles are emerging as a promising, cell-free therapeutic strategy for cardiac repair and regeneration following myocardial infarction.
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